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Anti-Ligand-dependent nuclear receptor-interacting factor 1 Antibody
产品别名
Anti-Ligand-dependent nuclear receptor-interacting factor 1 Antibody
Ligand-dependent nuclear receptor-interacting factor 1, LRIF1, RIF1, C1orf103, Receptor-interacting factor 1
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1), also known as RIF1, Receptor-interacting factor 1, and is encoded by the gene LRIF1/C1orf103/RIF1. The retinoic acid receptors (RARs) are ligand-dependent transcription factors that play critical roles in cell differentiation, embryonic development, and tumor suppression. RAR transcriptional activities are mediated by a growing family of nuclear receptor (NR) coregulators. Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is such a coregulator. Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is a repressor of ligand-induced transcriptional activity of retinoic receptor alpha. Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is ubiquitously expressed in a wide variety of tissues and cells and localizes exclusively to the nucleus and specifically to the nuclear matrix. |
Immunogen【免疫原】 | Epitope: Near C-terminus KLH-conjugated linear peptide corresponding to a region near the C-terminus of human Ligand-dependent nuclear receptor-interacting factor 1. |
Application【应用】 | Research Category Epigenetics & Nuclear Function Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected Ligand-dependent nuclear receptor-interacting factor 1 in HeLa, A431, HepG2, and NIH/3T3 cells. Research Sub Category Chromatin Biology This Anti-Ligand-dependent nuclear receptor-interacting factor 1 Antibody is validated for use in western blotting & ICC for the detection of Ligand-dependent nuclear receptor-interacting factor 1. |
Quality【质量】 | Evaluated by Western Blotting in SH-SY5Y cell lysate. Western Blotting Analysis: A 1:2,000 dilution of this antibody detected Ligand-dependent nuclear receptor-interacting factor 1 in 10 µg of SH-SY5Y cell lysate. |
Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | mouse, human |
species reactivity (predicted by homology) | primate (based on 100% sequence homology) |
concentration【浓度】 | 0.5 mg/mL |
technique(s) | immunocytochemistry: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_060842 |
UniProt accession no.【UniProt登记号】 | Q5T3J3 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~100 kDa observed |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |