Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^® 488 Conjugate

32160702

NA.45

Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^® 488 Conjugate is an antibody against Iba1/AIF1 for use in Immunohistochemistry.

Evaluated by Immunohistochemistry in human spleen tissue.

Immunohistochemistry Analysis: A 1:300 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.

Protein G Purified

Concentration: Please refer to lot specific datasheet.

100

mouse

ALEXA FLUOR^® 488

purified antibody

primary antibodies

20A12.1, monoclonal

mouse, human, rat

immunohistochemistry: suitable

IgG1κ

NP_001614

P55008

wet ice

human ... AIF1(199)

~17 kDa observed

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10 - Combustible liquids

WGK 2