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Anti-GJB2/Connexin 26 antibody produced in goat
| 产品编号： | 4108168 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-GJB2/Connexin 26 antibody produced in goat
Anti-CX26
Anti-Connexin 26
Anti-Gap junction protein
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Gap junction protein β 2 (GJB2) or connexin 26 (CX26) is a gap junction protein which is part of the connexin (Cx) family. It is expressed in epidermal keratinocytes and cochlea. The protein has four a-helical transmembrane domains, two extracellular loops, a cytoplasmic N-terminal domain and a C-terminal domain. The gene encoding GJB2 consists of two exons and is localized on human chromosome 13q12. |
| Immunogen【免疫原】 | Peptide with sequence YLLIRYCSGKSKKP from the C Terminus of the protein sequence according to NP_003995.2. |
| Application【应用】 | Anti-GJB2/Connexin 26 antibody produced in goat has been used in Western blotting. |
| Biochem/physiol Actions【生化/生理作用】 | Gap junction protein β 2 (GJB2) forms hexameric transmembrane channels called connexons, which is vital for gap junction communication. It has a role in the migration of cortical neurons during cortex development. GJB2 is involved in recycling potassium ions which is crucial for the hearing process. Mutations in the gene encoding this protein have been associated with skin disorders and sensorineural hearing loss. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | goat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | rat, mouse, human |
| technique(s) | indirect ELISA: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | P29033 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GJB2(2706) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
