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Anti-Delta3 Antibody, clone 1E7.2
产品别名
Anti-Delta3 Antibody, clone 1E7.2
Delta-like protein 3, Drosophila Delta homolog 3, Delta3
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | DLL3, also known as Delta like ligand 3, is a transmembrane Delta-like protein principally found in the Golgi apparatus and endosomes where it promotes Notch family receptor degradation to inhibit primary neurogenesis. DLL3 is one of five DSL proteins that bind to the Notch receptor. Notch signaling pathways play key roles in cell-fate determination and differentiation in many tissues during embryonic and postnatal development. Notch ligands family members are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in the DLL3 gene causes autosomal recessive spondylocostal dysostosis. |
| Immunogen【免疫原】 | Linear peptide corresponding to human Delta3. |
| Application【应用】 | Research Category Cell Structure Flow Cytometry Analysis: 0.1 µg from a representative lot detected Delta3 in HEK293 cells. This Anti-Delta3 Antibody, clone 1E7.2 is validated for use in WB, FC for the detection of Delta3. Research Sub Category ECM Proteins |
| Quality【质量】 | Evaluated by Western Blot in human liver tissue lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected Delta3 on 10 µg of human liver tissue lysate. |
| Physical form【外形】 | Purified by Ion-Exchange Chromatography Format: Purified Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control Human liver tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 1E7.2, monoclonal |
| species reactivity | human |
| technique(s) | flow cytometry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgMκ |
| NCBI accession no.【NCBI登记号】 | NP_058637 |
| UniProt accession no.【UniProt登记号】 | Q9NYJ7 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... DLL3(10683) |
产品说明
| Target description【目标描述】 | ~65 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
