Anti-DDX5/P68 RNA helicase antibody produced in goat

NA.41

DEAD-box helicase 5 (DDX5) is encoded by the gene mapped to human chromosome 17q23.3–q24.2.
DDX5 (DEAD, Asp-Glu-Ala-Asp, box helicase 5) is a multifunctional protein belonging to the DEAD box family of RNA helicases. It consists of twelve conserved motifs (including the signature D-E-A-D motif) forming a conserved ′helicase′ central domain, which plays an important role in the RNA metabolism.

Peptide with sequence C-PMIGYPMPTGYSQ from the C Terminus of the protein sequence according to NP_004387.1.

Anti-DDX5/P68 RNA helicase antibody produced in goat is suitable for indirect immunofluorescence, indirect ELISA, and western blot applications.

DDX5 (DEAD, Asp-Glu-Ala-Asp, box helicase 5) is associated with the regulation of pre-mRNA splicing mechanism. It acts as a transcriptional coactivator to control alternative splicing during the formation of spliceosome. DDX5 provides stability to the RNA secondary structure during several activities such as in the translation initiation, nuclear and mitochondrial splicing. It facilitates the unwinding as well as detachment of protein part from RNA. The protein also participates in the estrogen- and androgen-signaling pathway.

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Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

100

goat

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

human, mouse, rat

immunohistochemistry: suitable
indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: suitable

P17844

dry ice

−20℃

human ... DDX5(1655)

GHS07

Warning

H315 - H319

P305 + P351 + P338

Eye Irrit. 2 - Skin Irrit. 2

12 - Non Combustible Liquids

WGK 2