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Anti-DARC Antibody
| 产品编号： | 4106879 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-DARC Antibody
DARC Antibody, Duffy antigen, Fy glycoprotein, GpFy, Cell adhesion molecule 3, CADM3
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Duffy antigen/chemokine receptor (DARC), also known as Fy glycoprotein (GpFy), is a multi-pass membrane protein belonging to the G-protein coupled receptor Duffy family. DARC binds, with high affinity, several chemokines without transducing any signal, suggesting it may modulate the signals normally induced by these chemokines. DARC is found in adult kidney, adult spleen, bone marrow, and fetal liver. It is expressed along postcapillary venules throughout the body, except in the adult liver. |
| Specificity【特异性】 | This antibody recognizes the C-terminus of DARC. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the C-terminus of human DARC. Epitope: C-terminus |
| Application【应用】 | Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected DARC in mouse brain tissue. Research Category Neuroscience Research Sub Category Developmental Neuroscience Detect Duffy antigen/chemokine receptor using this rabbit polyclonal antibody, Anti-DARC Antibody validated for use in western blotting & IHC (Paraffin). |
| Quality【质量】 | Evaluated by Western Blotting in mouse brain tissue lysate. Western Blotting Analysis: 2 µg/mL of this antibody detected DARC in 15 µg of mouse brain tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control Mouse brain tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse |
| species reactivity (predicted by homology) | human (immunogen homology) |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q16570 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~23 and 35 kDa observed. Uniprot describes two isoforms at ~35 and ~36 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
