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Anti-CYP3A4 antibody produced in rabbit

产品编号:4106806
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4106806100 μL4310
产品别名

Anti-CYP3A4 antibody produced in rabbit

CYP3A3

NF-25

CP34

P450C3

P450PCN1

CYP3A

CYPIIIA3

CP33

CYP3A4

HLP

CYPIIIA4

产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
57
species reactivity
human, rat, mouse
concentration【浓度】
0.77 mg/ml
technique(s)
immunofluorescence: 1:20-1:100
immunohistochemistry: 1:20-1:50
western blot: 1:500-1:1000
UniProt accession no.【UniProt登记号】
P08684
shipped in【运输】
wet ice
storage temp.【储存温度】
2-8℃
Gene Information
human ... CYP3A4(1576)
基本信息
General description【一般描述】
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
Immunogen【免疫原】
Recombinant fusion protein containing a sequence corresponding to amino acids 244-503 of human CYP3A4 (NP_059488.2).
Physical form【外形】
PBS with 0.02% sodium azide,pH7.3.
产品说明
Storage and Stability【储存及稳定性】
Store at 4℃. Avoid freeze / thaw cycles.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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