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产品别名
Anti-CYP3A4 antibody produced in rabbit
CYP3A3
NF-25
CP34
P450C3
P450PCN1
CYP3A
CYPIIIA3
CP33
CYP3A4
HLP
CYPIIIA4
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 57 |
| species reactivity | human, rat, mouse |
| concentration【浓度】 | 0.77 mg/ml |
| technique(s) | immunofluorescence: 1:20-1:100 immunohistochemistry: 1:20-1:50 western blot: 1:500-1:1000 |
| UniProt accession no.【UniProt登记号】 | P08684 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | human ... CYP3A4(1576) |
基本信息
| General description【一般描述】 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Immunogen【免疫原】 | Recombinant fusion protein containing a sequence corresponding to amino acids 244-503 of human CYP3A4 (NP_059488.2). |
| Physical form【外形】 | PBS with 0.02% sodium azide,pH7.3. |
产品说明
| Storage and Stability【储存及稳定性】 | Store at 4℃. Avoid freeze / thaw cycles. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
