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Anti-CX3CL1 Antibody
| 产品编号： | 4106770 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-CX3CL1 Antibody
Fractalkine, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1, FKN, NTT, SCYD1, A-152E5.2
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | C-X3-C motif chemokine 1 (CX3CL1), also known as CX3C membrane-anchored chemokine, Neurotactin (NTT), Small-inducible cytokine D1 (SCYD1), and Fractalkine (FKN), is a CX3C chemokine known to induce adhesion and migration of leukocytes. Recent studies have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-alpha in activated microglia and neuronal cells, and it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Other evidence suggests that CX3CL1 may play a role in regulating leukocyte adhesion and migration processes at the endothelium. Additionally, CX3CL1 is implied to inhibit CX3CR1, which is a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection. CX3CL1 is expressed in small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human CX3CL1. |
| Application【应用】 | Research Category Neuroscience Research Sub Category Developmental Neuroscience Anti-CX3CL1 Antibody is a highly specific rabbit polyclonal antibody, that targets CX3CL1 & has been tested in western blotting. |
| Quality【质量】 | Evaluated by Western Blotting in C2C12 cell lysate. Western Blotting Analysis: 2 µg/mL of this antibody detected CX3CL1 in 15 µg of C2C12 cell lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control C2C12 cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse |
| species reactivity (predicted by homology) | human (immunogen homology) |
| technique(s) | western blot: suitable |
| UniProt accession no.【UniProt登记号】 | P78423 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~50 kDa observed. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
