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Anti-Choline Acetyltransferase Antibody
产品别名
Anti-Choline Acetyltransferase Antibody
ChAT
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Acetylcholine (ACh) is a common neurotransmitter for motoneurons, preganglionic autonomic neurons, postganglionic parasympathetic neurons, a variety of brain regions and some emerging neuron-like stem cells. The metabolism of Ach is relatively simple, involving only two enzymes: choline acetyltransferase (ChAT) for synthesis and acetylcholinesterase (AChE) for degradation. Further, acetylcholine has little function in neurons other than neurotransmission and seems to be neuron specific. It seems that only cholinergic neurons have significant amounts of ChAT making anti-cholinacetyltransferase a useful specific marker. |
Specificity【特异性】 | Recognizes cholinergic neurons in brain and central nervous systems. |
Immunogen【免疫原】 | Human placental enzyme. |
Application【应用】 | Immunoblot: 1:1,000-1:5,000 Immunohistochemistry: 1:500-1:1,000. See page two of this data sheet. Optimal working dilutions must be determined by the end user. Research Sub Category Neurotransmitters & Receptors Neuronal & Glial Markers Research Category Neuroscience Anti-Choline Acetyltransferase Antibody is an antibody against Choline Acetyltransferase for use in IH & WB. |
Physical form【外形】 | Unpurified Goat antisera, liquid, no preservatives. |
Analysis Note【分析说明】 | Control Rat brain tissue |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | goat |
antibody form【抗体形式】 | serum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
species reactivity | rat, guinea pig, mouse |
manufacturer/tradename | Chemicon® |
technique(s) | immunohistochemistry: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NM_020549.3 NM_020984.2 NM_020985.2 NM_020986.2 |
UniProt accession no.【UniProt登记号】 | P28329 |
shipped in【运输】 | dry ice |
产品说明
Target description【目标描述】 | 70 kDa |
Storage and Stability【储存及稳定性】 | Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |