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Anti-BCAR3 Antibody, clone 9D9.1
产品别名
Anti-BCAR3 Antibody, clone 9D9.1
Breast cancer anti-estrogen resistance protein 3, Novel SH2-containing protein 2, SH2 domain-containing protein 3B
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Breast cancer anti-estrogen resistance protein 3 (BCAR3), also known as Novel SH2-containing protein 2 (NSP2) and SH2 domain-containing protein 3B (SH2D3B) is an adapter protein that regulates the proliferation in breast cancer cells. BCAR3 may also be regulated by cellular adhesion to extracellular matrix proteins. BCAR3 is found in several cancer cell lines; however, it is not found in nonmalignant breast tissue. When BCAR3 is overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to human BCAR3. |
| Application【应用】 | Research Category Cell Structure Anti-BCAR3, clone 9D9.1 is an antibody against BCAR3 for use in Western Blotting. Research Sub Category Adhesion (CAMs) |
| Quality【质量】 | Evaluated by Western Blotting in U2OS cell lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected BCAR3 in 10 µg of U2OS cell lysate. |
| Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
| Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 9D9.1, monoclonal |
| species reactivity | human |
| technique(s) | western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_001248337 |
| UniProt accession no.【UniProt登记号】 | O75815 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... BCAR3(8412) |
产品说明
| Target description【目标描述】 | ~93 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
