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Anti-BCAR3 Antibody
产品编号: | 4105328 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-BCAR3 Antibody
Breast cancer anti-estrogen resistance 3, NSP2, SH2D3B, Novel SH2-containing protein 2, SH2 domain-containing protein 3B, BCAR
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Breast cancer anti-estrogen resistance protein 3 (BCAR3), also known as Novel SH2-containing protein 2 (NSP2) and SH2 domain-containing protein 3B (SH2D3B) is an adapter protein that regulates the proliferation in breast cancer cells. BCAR3 may also be regulated by cellular adhesion to extracellular matrix proteins. BCAR3 is found in several cancer cell lines; however, it is not found in nonmalignant breast tissue. When BCAR3 is overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human BCAR3. |
Application【应用】 | Anti-BCAR3 Antibody is a highly specific rabbit polyclonal antibody, that targets Breast cancer Anti-estrogen resistance protein 3 & has been tested in western blotting. Research Category Apoptosis & Cancer |
Quality【质量】 | Evaluated by Western Blotting in mouse kidney tissue lysate. Western Blotting Analysis: 1 µg/mL of this antibody detected BCAR3 in 15 µg of mouse kidney tissue lysate. |
Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. Antigen Affinity Purified |
Analysis Note【分析说明】 | Control Mouse kidney tissue lysate |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | mouse |
species reactivity (predicted by homology) | human (immunogen homology) |
technique(s) | western blot: suitable |
UniProt accession no.【UniProt登记号】 | O75815 |
shipped in【运输】 | wet ice |
Gene Information | human ... BCAR3(8412) |
产品说明
Target description【目标描述】 | ~104 kDa observed |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 2 |