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Anti-ApoA4 Antibody
| 产品编号： | 4104947 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-ApoA4 Antibody
Apolipoprotein A4, Apolipoprotein A-IV, ApoA-IV, APO-AIV, ApoA4
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | ApoA4, also known as Apolipoprotein A4 or ApoA-IV, is a member of the apolipoprotein A1/A4/E family. ApoA4 is a major component of HDL and it can be found on the surface of newly synthesized chylomicrons. Studies have shown that APoA4 is required for efficient activation of lipoprotein lipase by ApoC-II, which is a potent activator of Lecithin Cholesterol Acyltransferase (LCAT). Other evidence points out that ApoA4 may have a role in chylomicrons and VLDL secretion and catabolism. The physiological function of ApoA4 is not confirmed yet, but evidence from several in vitro studies indicate that it may play a role in the reverse cholesterol transport pathway, transporting cholesterol from peripheral cells back to the liver. ApoA4 is synthesized primarily in the intestine and secreted in the plasma. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human ApoA4. |
| Application【应用】 | Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected ApoA4 in human colon tissue. Research Sub Category Lipid Metabolism & Weight Regulation Research Category Signaling Anti-ApoA4 Antibody is a highly specific rabbit polyclonal antibody, that targets Apolipoprotein A & has been tested in western blotting & IHC. |
| Quality【质量】 | Evaluated by Western Blotting in human liver tissue lysate. Western Blotting Analysis: 2 µg/mL of this antibody detected ApoA4 in 15 µg of human liver tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control Human liver tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | P06727 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... APOA4(337) |
产品说明
| Target description【目标描述】 | ~38 kDa observed. Uncharacterized bands may appear in some lysate(s). |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
