sCD27 Ligand human

NA.32

CD27 Ligand, a type II transmembrane protein, is a member of the TNF superfamily. It is expressed on activated T and B lymphocytes as well as NK cells. CD27L and its receptor (CD27) regulate the immune response by promoting T-cell expansion and differentiation, as well as NK enhancement. CD27 signaling can act as a co-stimulatory effector to sustain the survival of CD8+ T cells, primarily by inducing increased expression of the IL-2 gene. Full length human CD27L is a 193 amino acid protein, consisting of a 17 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 155 amino acid extracellular domain. Human soluble CD27L corresponds to the 155 amino acid extracellular domain of the full length CD27L protein. Therecombinant human sCD27L contains the extracellular domain plus an N-terminal His-Tag.

Sterile filtered through a 0.2 micron filter. Lyophilized from 20 mM Sodium Citrate, pH 3.0.

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃.

human

expressed in E. coli

≥95% (SDS-PAGE)

lyophilized powder

19.2 kDa

pkg of 10 μg
pkg of 50 μg

<1 EU/μg endotoxin (LAL test)

P26842

wet ice

−20℃

human ... CD27(939)

10 - Combustible liquids

WGK 1