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产品别名
Anti-p53 antibody produced in rabbit
BCC7
TP53
BMFS5
TRP53
LFS1
P53
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 23-43 |
species reactivity | rat, human |
concentration【浓度】 | 1.31 mg/ml |
technique(s) | ChIP: 1:50-1:100 immunofluorescence: 1:50-1:200 immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000 |
UniProt accession no.【UniProt登记号】 | P04637 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... TP53(7157) |
基本信息
General description【一般描述】 | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). |
Immunogen【免疫原】 | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human p53 (NP_000537.3). |
Physical form【外形】 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
产品说明
Storage and Stability【储存及稳定性】 | Store at -20℃. Avoid freeze / thaw cycles. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |