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Anti-CD117 Antibody, clone ACK2
产品别名
Anti-CD117 Antibody, clone ACK2
c-kit, SCF Receptor
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | This 145 kDa molecule is a member of the tyrosine kinase receptor family and is expressed by a majority of hematopoietic progenitor cells. The interaction of the mouse c-kit receptor and steel factor promotes proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells, and plays a role in signaling and activation of these cells. |
Specificity【特异性】 | Specifically recognizes mouse CD117, known as c-kit receptor, stem cell factor receptor and steel factor receptor. |
Application【应用】 | Flow Cytometry: 0.2 μg per 10e6 cells Immunoprecipitation Immunohistochemistry (Frozen) Western blot Blocking Ligand Binding Optimal working dilutions must be determined by the end user. Detect CD117 using this Anti-CD117 Antibody, clone ACK2 validated for use in FC, IH, IP, FUNC & WB. Research Category Stem Cell Research Research Sub Category Hematopoietic Stem Cells Mesenchymal Stem Cells |
Linkage【联系】 | Replaces: CBL1360P |
Physical form【外形】 | Format: Purified The monoclonal is presented in phosphate buffered saline containing 10mM sodium azide. Protein A purified |
Analysis Note【分析说明】 | Control Skin tissue, normal breast epithelium, melanocytes, mast cells and glial cells |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | rat |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | ACK2, monoclonal |
species reactivity | mouse |
manufacturer/tradename | Chemicon® |
technique(s) | flow cytometry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
input | sample type hematopoietic stem cell(s) sample type mesenchymal stem cell(s) |
isotype【同位素/亚型】 | IgG2bκ |
NCBI accession no.【NCBI登记号】 | NM_000222.2 NM_001093772.1 |
UniProt accession no.【UniProt登记号】 | P10721 |
shipped in【运输】 | wet ice |
Gene Information | human ... KIT(3815) |
产品说明
Target description【目标描述】 | 145 kDa |
Storage and Stability【储存及稳定性】 | For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |