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TRAIL human
| 产品编号： | 4096570 |
| 规格： | recombinant, expressed in NSO cells, >97% (SDS-PAGE), lyophilized powder |
| CAS NO： | 2244730-93-4 |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4096570 | 10 μG | 8620 |
产品别名
2244730-93-4
TRAIL human
TL2
Apo2 Ligand
Apo2L
TNF-related apoptosis-inducing ligand
基本信息
| MDL number | MFCD01867158 |
| NACRES | NA.32 |
| Application【应用】 | TRAIL human was used to induce cytotoxicity in A549, a human lung carcinoma cell line. |
| Biochem/physiol Actions【生化/生理作用】 | Type II transmembrane protein of the TNF superfamily. Ligand for apoptosis-inducing death receptors DR4 and DR5, decoy receptors DcR1 and DcR2, and osteoprotegerin. Approximately 28% amino acid sequence identity to FAS ligand. Human and mouse TRAIL share 65% sequence identity. TNF-related apoptosis-inducing ligand (TRAIL) is a type II transmembrane protein that belongs to TNF family. It is present in both soluble as well as membrane-bound form and can induce rapid apoptosis of various transformed cell lines but not the normal cells. Additionally, the product can also induces apoptotic cell death in TRAIL-sensitive U343MGcells. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.5 mg bovine serum albumin. |
| Analysis Note【分析说明】 | Induces cytotoxicity in mouse L-929 cells in the presence of actinomycin D. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in NSO cells |
| description【描述】 | N-terminal 6X histidine-tagged extracellular domain |
| Assay【测定】 | >97% (SDS-PAGE) |
| form【形式】 | lyophilized powder |
| mol wt【分子量】 | 24 kDa by SDS-PAGE predicted mol wt ~21 kDa |
| technique(s) | cell culture | mammalian: suitable |
| impurities【杂质】 | endotoxin, tested |
| UniProt accession no.【UniProt登记号】 | P50591 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... TNFSF10(8743) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
