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Anti-Sodium Channel NaV1.8 antibody produced in rabbit
产品编号: | 4096446 |
规格: | affinity isolated antibody, lyophilized powder |
包装规格: | 50 μL,200 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Sodium Channel NaV1.8 antibody produced in rabbit
Anti-SCN10A
Anti-PN3
基本信息
MDL number | MFCD08705520 |
NACRES | NA.41 |
General description【一般描述】 | Sodium voltage-gated channel α subunit 10 (SCN10A) codes for Nav1.8 sodium channels. It is expressed in nociceptive neurons. This gene is mapped to human chromosome 3p22.2. |
Immunogen【免疫原】 | peptide (C)EDEVAAKEGNSPGPQ corresponding to residues 1943-1957 of rat Nav1.8. This sequence has 14/15 residues identical in mouse and 7/15 residues identical in human. |
Application【应用】 | Anti-Sodium Channel NaV1.8 antibody has been used in immunohistochemistry and immunocytochemistry. |
Biochem/physiol Actions【生化/生理作用】 | Sodium voltage-gated channel α subunit 10 (SCN10A) plays a major role in human pain. It is involved in the pathophysiology of cerebellar deficits in MS (multiple sclerosis). |
Physical form【外形】 | Lyophilized from phosphate buffered saline, pH 7.4, with 1% bovine serum albumin, and 0.05 % sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | lyophilized powder |
species reactivity | rat |
technique(s) | immunohistochemistry (frozen sections): suitable using adult rat DRG western blot: 1:200 using rat DRG lysates |
UniProt accession no.【UniProt登记号】 | Q62968 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... SCN10A(6336) mouse ... Scn10a(20264) rat ... Scn10a(29571) |
产品说明
Target description【目标描述】 | Anti-Sodium Channel NaV1.8 specifically recognizes NaV1.8. Voltage-gated sodium channels (VGSCs) are present in most excitable cells. They play a crucial role in regulating the cell excitability, being primarily responsible for the |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | nwg |