Anti-Myelin Associated Glycoprotein Antibody, clone 513

32160702

NA.41

Myelin-associated glycoprotein (MAG),a member of the immunoglobulin superfamily, is a membrane glycoprotein of 100 kDa, and is thought to be involved in the process of myelination. Axonal regeneration in the adult central nervous system (CNS) is limited by two proteins in myelin, Nogo and MAG. MAG has been implicated in the inhibition of nerve regeneration in the CNS.

Detects Myelin Associated Glycoprotein (MAG) in immunohistochemistry on frozen sections, immunocytochemistry and Western blot (under non-reducing conditions). MAB1567 is useful for myelinogenesis and multiple sclerosis studies.

L2 epitope carrying glycoprotein extract of 1-2 day old chicken brain.

Detect Myelin Associated Glycoprotein using this Anti-Myelin Associated Glycoprotein Antibody, clone 513 validated for use in IC, IH & WB.
Research Sub Category
Neuronal & Glial Markers

Neurochemistry & Neurotrophins
Research Category
Neuroscience
Western Blot:
20 μg/mL of a previous lot was used on western blot under non-reducing conditions only.{See Ellezam, 2003}

Immunocytochemistry:
5-10 µg/mL of a previous lot was used, methanol fixation required.

Optimal working dilutions must be determined by end user.

Evaluated by immunohistochemistry on rat hippocampus.

Immunohistochemistry(paraffin):
Representative image from a previous lot.
Mouse anti-Myelin Associated Glycoprotein [MAG] (Catalog Number MAB1567) localization of MAG in rat hippocampus. Photo courtesy of Dr. Robert Sloviter, University of Arizona.

Format: Purified
Protein A purified
Purified mouse monoclonal IgG1 in buffer containing 10 mM potassium phosphate buffer, 50 mM NaCl, pH 7.5. Contains no preservative.

Control
Rat hippocampus tissue, rat brain lysate, PC12 cells.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

100

mouse

purified immunoglobulin

primary antibodies

513, monoclonal

rat, chicken, mouse, human, bovine, frog

Chemicon^®

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

IgG1

NM_002361.2

P20916

dry ice

100 kDa

Stable for 1 year at -20ºC from date of receipt.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

10 - Combustible liquids

WGK 2