Milli-Mark^® Anti-CD64-PE Antibody, clone 10.1

32160702

NA.44

CD64 is the high-affinity IgG Fc receptor belonging to the immunoglobulin supergene family (Guyre, 2002). CD64 is a 72 kDa glycoprotein which binds monomeric IgG (human IgG>>IgG>>>IgG4>>>IgG2 and mouse IgG3>IgG2a>>>IgG1, IgG2b). Three genes: FcγR1A, FcγR1B and FcγR1C, which have >98 percent identity at the nucleotide level, have been identified and mapped to chromosome 1, band q21.1 (Sun,1997)). The FcγR1A gene, which specified the high-affinity IgG receptor, encodes three C2-type Ig-like extracellular domains, a 21 amino acid transmembrane region, and a charge cytoplasmic tail of 61 amino acids (Sun, 1997)(van de Winkel,1993).

Antibody recognizes Human CD64 antigen.

Human rheumatoid synovial fluid cells and monocytes.

Milli-Mark Anti-CD64-PE Antibody, clone 10.1 detects level of CD64 & has been published & validated for use in FC.
Research Sub Category
Immunoglobulins & Immunology
Research Category
Inflammation & Immunology

Evaluated by flow cytometry using human PBMCs

Protein A purified
Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Control
PBMC′s

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

100

mouse

PE

purified immunoglobulin

primary antibodies

10.1, monoclonal

human

Milli-Mark^®

flow cytometry: suitable

IgG1κ

NP_000034.1

P12314

wet ice

72 kDa (Sun W, 1997)

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

12 - Non Combustible Liquids

WGK 2