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C6-NBD Galactosyl Ceramide
产品编号: | 4095887 |
规格: | N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-galactosyl-β1-1′-sphingosine, powder |
CAS NO: | 170212-26-7 |
包装规格: | 250 μG |
产品类别: | 进口试剂 |
品牌: | Avanti |
优惠价: | 立即咨询 |
产品别名
170212-26-7
C6-NBD Galactosyl Ceramide
基本信息
Empirical Formula【经验(实验)分子式】 | C36H59N5O11 |
Molecular weight | 737.88 |
NACRES | NA.25 |
General description【一般描述】 | C6-NBD Galactosyl Ceramide is a fluorescent analog of the sphingolipid, galactosyl ceramide. Its fluorescent property is due to presence of NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) group. |
Application【应用】 | C6-NBD Galactosyl Ceramide is suitable for use as a substrate in neutral β-glycosylceramidase (GCase) activity assay. |
Biochem/physiol Actions【生化/生理作用】 | Galactosyl ceramide is also known as galactocerebroside and is produced in the lumen of the endoplasmic reticulum. Galactosyl ceramide is a vaccine adjuvant, it stimulates natural killer T (NKT) cells to increase secretion of T helper type 1 (Th1) and T-helper type 2 (TH2) cytokines. Galactosyl ceramide accumulation in excess is responsible for diseases such as Krabbe′s disease. Galactocerebroside is a precursor of 3′-sulfo-galactosylceramide, a vital sulfoglycolipid found in the brain and other organs. |
产品性质
Assay【测定】 | >99% (TLC) |
form【形式】 | powder |
manufacturer/tradename | Avanti Polar Lipids 810220P |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (810220P-250ug) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |