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FF-MAS

产品编号:4095739
规格:14-demethyl-14-dehydrolanosterol, powder
CAS NO:64284-64-6
包装规格:1 MG
产品类别:进口试剂
品牌:Avanti
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
40957391 MG8440
产品别名

64284-64-6

FF-MAS

4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol; follicular fluid meiosis-activating sterol

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C29H46O
Molecular weight
410.67
NACRES
NA.25
General description【一般描述】
Follicular fluid meiosis-activating sterol (FF-MAS) is an intermediate in the cholesterol biosynthetic pathway present in all cells, and may represent the physiological signal that instructs the oocyte to reinitiate meiosis.
Application【应用】
FF-MAS has been used:
  • as a standard in gas chromatography/ mass spectroscopy (GC/MS) for profiling sterols of oligodendrocyte progenitor cells (OPCs)
  • as Dulbecco′s modified eagle medium (DMEM) medium supplement to test its effect on cancer cell viability
  • to evaluate its effect on LXRβ-overexpressing squamous carcinoma SCC61 cells

Biochem/physiol Actions【生化/生理作用】
14-demethyl-14-dehydrolanosterol (FF-MAS) was first identified in follicular fluid of women and plays a key role in oocyte nuclear maturation. The levels of FF-MAS may be regulated by cytochrome P450 family 27 subfamily A member 1. Supplementation of FF-MAS to oocytes promotes meiotic maturation favoring preimplantation. However, FF-MAS has low solubility and is metabolized to cholesterol rapidly.
产品性质
Assay【测定】
>99% (TLC)
form【形式】
powder
manufacturer/tradename
Avanti Polar Lipids 700077P
shipped in【运输】
dry ice
storage temp.【储存温度】
−70℃
InChI
1S/C29H46O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,13,20,22,25-26,30H,8,10-12,14-18H2,1-7H3/t20-,22-,25+,26+,28-,29-/m1/s1
InChI key
LFQXEZVYNCBVDO-PBJLWWPKSA-N
packaging【包装】
5 mL Amber Glass Screw Cap Vial (700077P-1mg)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
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