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12:0 EPC (Cl Salt)
产品编号: | 4095585 |
规格: | 1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (chloride salt), powder |
CAS NO: | 474945-22-7 |
包装规格: | 10 MG |
产品类别: | 进口试剂 |
品牌: | Avanti |
优惠价: | 立即咨询 |
产品别名
474945-22-7
12:0 EPC (Cl Salt)
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C34H69NO8PCl |
Molecular weight | 686.34 |
NACRES | NA.25 |
General description【一般描述】 | 1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (12:0 EPC) is a cationic phospholipid. 12:0 EPC is a short-chain analog of dioleoyl ethylphosphatidylcholine. O-alkyl phosphatidylcholines constitute the first chemically stable triesters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable. |
Application【应用】 | 1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (12:0 EPC (Cl Salt)) is suitable for use in lipoplex preparation and to study the lipoplex transfection activity. It might also be used in lipid mixtures to study its cubic phases of formation, stability and phase transitions. |
Biochem/physiol Actions【生化/生理作用】 | 1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (12:0 EPC) is preferred for transfection of cultured primary endothelial cells. 12:0 EPC forms lamellar lipoplexes possessing high to superior transfection activity. Chemically synthesized cationic lipids are applicable as non-viral gene carriers. Variation in the hydrocarbon chain of phosphatidylcholine (PC) derivatives affects transfection efficiency. |
产品性质
form【形式】 | powder |
manufacturer/tradename | Avanti Polar Lipids 890700P |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
SMILES string | O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)OCC.[Cl-] |
packaging【包装】 | 5 mL Clear Glass Sealed Ampule (890700P-10mg) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |