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PTP-β human
| 产品编号： | 4095555 |
| 规格： | ≥90%, recombinant, expressed in E. coli K12, GST-tagged, buffered aqueous glycerol solution, ≥50,000 units/mg protein |
| CAS NO： | 300853-81-0 |
| 包装规格： | 10000 UNITS |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
300853-81-0
PTP-β human
Protein Tyrosine Phosphatase-β
基本信息
| MDL number | MFCD02688688 |
| NACRES | NA.32 |
| General description【一般描述】 | Protein tyrosine phosphatase, receptor type B (PTPRB), also known as vascular endothelial-protein-tyrosine phosphatase (VE-PTP), might have a role in remodeling of blood vessels and in angiogenesis. The gene encoding it is localized on human chromosome 12q15. It is also important for endothelial cell migration. The protein also controls the phosphorylation state of the angiopoietin receptor, Tie-2. PTPRB may modulate sodium channels by influencing the tyrosine phosphorylation status. |
| Biochem/physiol Actions【生化/生理作用】 | Dephosphorylates tyrosine proteins. |
| Unit Definition【单位定义】 | One unit of PTP-β will hydrolyze 1.0 nanomole of p-nitrophenyl phosphate per min at 30 ℃. |
| Physical form【外形】 | solution in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCL, 3 mM DTT, 16 mM glutathione and 20% glycerol |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli K12 |
| Assay【测定】 | ≥90% |
| form【形式】 | buffered aqueous glycerol solution |
| Specific Activity | ≥50,000 units/mg protein |
| mol wt【分子量】 | ~250 kDa |
| UniProt accession no.【UniProt登记号】 | P23467 |
| application(s) | cell analysis |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... PTPRB(5787) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
