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PhotoClick Cholesterol
产品编号: | 4095536 |
规格: | Hex-5′-ynyl 3β-hydroxy-6-diazirinyl-5α-cholan-24-oate, powder |
CAS NO: | 1485490-47-8 |
包装规格: | 100 μG,250 μG |
产品类别: | 进口试剂 |
品牌: | Avanti |
优惠价: | 立即咨询 |
产品别名
1485490-47-8
PhotoClick Cholesterol
hex-5-yn-1-yl 4-((3S,5S)-3-hydroxy-10, 13-dimethyl-1,2,3,4,5,7,8,9,10,11,12,13,14,15,16,17-hexadecahydrospiro[cyclopenta[a]phenanthrene-6,3′-diazirin]-17-yl)pentanoate
基本信息
Empirical Formula【经验(实验)分子式】 | C30H46N2O3 |
Molecular weight | 482.70 |
NACRES | NA.25 |
General description【一般描述】 | PhotoClick Cholesterol is a clickable, photoreactive sterol probe for use in combination with quantitative mass spectrometry to globally map cholesterol-protein interactions directly in living cells. In addition to the UV-activatable cross-linking diazirine group that reacts with proteins, the sterol contains an alkyne group for incorporation of reporter and affinity tags through click-chemistry. PhotoClick Cholesterol is a synthetic analog of cholesterol and is photoreactive. It comprises the alkyne group. |
Application【应用】 | PhotoClick Cholesterol has been used:
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Biochem/physiol Actions【生化/生理作用】 | PhotoClick Cholesterol serves as a probe for tracking cholesterol-binding proteins. The copper-catalyzed azide-alkyne cycloaddition is the basis for its probe functionality. The alkyne group is essential for the click chemistry property. Its binding to partners is mediated by photocrosslinking. |
产品性质
Assay【测定】 | >99% (TLC) |
form【形式】 | powder |
manufacturer/tradename | Avanti Polar Lipids 700147P |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 2 mL Amber Serum Vial with Stopper and Crimp Cap (700147P-250ug) 2 mL Amber Serum Vial with Stopper and Crimp Cap (700147P-100ug) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |