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18:0-20:4 PI(4,5)P2
产品编号: | 4095498 |
规格: | 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′,5′-bisphosphate) (ammonium salt), powder |
CAS NO: | 799268-59-0 |
包装规格: | 100 μG,500 μG |
产品类别: | 进口试剂 |
品牌: | Avanti |
优惠价: | 立即咨询 |
产品别名
799268-59-0
18:0-20:4 PI(4,5)P2
1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-[phosphoinositol-4,5-bisphosphate] (ammonium salt); PIP2[4′,5′](18:0/20:4(5Z,8Z,11Z,14Z))
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C47H94N3O19P3 |
Molecular weight | 1098.18 |
NACRES | NA.25 |
General description【一般描述】 | Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT. Phosphatidylinositol 4,5-bisphosphate (PIP2) is a negatively charged phospholipid, abundant in the plasma membrane. |
Application【应用】 | 18:0-20:4 PI(4,5)P2 or 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′,5′-bisphosphate) (ammonium salt) has been used:
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产品性质
Assay【测定】 | >99% (TLC) |
form【形式】 | powder |
manufacturer/tradename | Avanti Polar Lipids 850165P |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
SMILES string | [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+] |
packaging【包装】 | 2 mL Amber Serum Vial with Stopper and Crimp Cap (850165P-100ug) 2 mL Amber Serum Vial with Stopper and Crimp Cap (850165P-500ug) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |