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Human Epidermal Keratinocytes: HEK, neonatal
基本信息
| NACRES | NA.81 |
| General description【一般描述】 | Epidermal keratinocytes comprise 90 % of all cells found in the epidermis, the outermost layer of skin. They produce keratin, the intermediate filament, largely responsible for skin′s barrier function. Through their interactions with epidermal melanocytes, keratinocytes obtain melanin and store it as a means of protection from UV radiation. HEK provide an excellent model system to study many aspects of epithelial function and disease, particularly those related to skin biology and toxicology, as well as HPV infection. When grown on inserts and provided with the liquid/air interface, HEK can differentiate into a stratified squamous epithelium and serve as a more physiological 3D tissue model for in vitro studies. |
| Cell Line Origin【细胞系来源】 | Skin |
| Application【应用】 | Skin biology and toxicology, wound healing, artificial skin, cell proliferation, migration, UV light response |
| Components【组分】 | Basal Medium containing 10% FBS & 10% DMSO |
| Preparation Note【制备说明】 |
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| Subculture Routine【传代培养常规】 | Please refer to the HEK Culture Protocol. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | human neonatal foreskin or adult skin (normal) |
| packaging【包装】 | pkg of 500,000 cells |
| growth mode【生长模式】 | Adherent |
| karyotype【核型】 | 2n = 46 |
| morphology【形态学】 | Epidermal |
| technique(s) | cell culture | mammalian: suitable |
| relevant disease(s)【相关疾病】 | allergies; cancer |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −196℃ |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
