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LYN B, active, GST tagged human
| 产品编号： | 4094319 |
| 规格： | PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
LYN B, active, GST tagged human
JTK8
p65
基本信息
| NACRES | NA.32 |
| Biochem/physiol Actions【生化/生理作用】 | LYN (proto-oncogene) belongs to the src family of tyrosine kinases. It controls cancer cell growth, migration, invasion and survival. Upregulation of LYN is associated with shorter overall survival in breast cancer. LYN shows anti- or pro-apoptotic effects. It can enhance AKT (v-akt murine thymoma viral oncogene homolog) phosphorylation or suppress AKT activation. It is also responisble for activation of p58 PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase). Activation of LYN-PI3K-AKT signaling enhances myeloma proliferation. |
| Physical form【外形】 | Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol. |
| Legal Information【法律信息】 | PRECISIO is a registered trademark of sigma-aldrich Co. LLC |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in baculovirus infected Sf9 cells |
| product line【产品线】 | PRECISIO® Kinase |
| Assay【测定】 | ≥70% (SDS-PAGE) |
| form【形式】 | buffered aqueous glycerol solution |
| Specific Activity | 205-277 nmol/min·mg |
| mol wt【分子量】 | ~85 kDa |
| UniProt accession no.【UniProt登记号】 | Q02218 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... LYN(4967) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
