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Heregulin-β1 (EGF Domain) human
| 产品编号： | 4093804 |
| 规格： | ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder |
| 包装规格： | 10 μG，50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Heregulin-β1 (EGF Domain) human
HRG-β1
基本信息
| MDL number | MFCD03457066 |
| NACRES | NA.32 |
| Biochem/physiol Actions【生化/生理作用】 | Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases. The binding of HRG results in receptor dimerization and receptor trans-autophosphorylation. The phosphorylated receptors recruit cellular signaling proteins, initiating signaling pathways. |
| Analysis Note【分析说明】 | The biological activity is measured by its ability to stimulate the proliferation of human MCF-7 cells grown under serum-free conditions. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥98% (SDS-PAGE) |
| form【形式】 | lyophilized powder |
| potency【效能】 | <0.50 ng/mL |
| mol wt【分子量】 | predicted mol wt 8 kDa |
| packaging【包装】 | pkg of 10 and 50 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| impurities【杂质】 | endotoxin, tested |
| color【颜色】 | white |
| UniProt accession no.【UniProt登记号】 | Q02297 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... NRG1(3084) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
