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Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide)
| 产品编号： | 4093001 |
| 规格： | PEG average Mn 5,000, PLGA average Mn 10,000, lactide:glycolide 80:20 |
| 包装规格： | 1 G |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide)
PEG-PLGA
mPEG-b-PLGA
PEG5K-PLGA10K
结构式
基本信息
| Linear Formula【线性分子式】 | H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nCH3 |
| Application【应用】 | This polymer is a amphiphilic diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. This biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. |
产品性质
| form【形式】 | powder |
| feed ratio【投料比】 | lactide:glycolide 80:20 |
| mol wt【分子量】 | PEG average Mn 5,000 (by NMR) PLGA average Mn 10,000 (by NMR) |
| impurities【杂质】 | ≤500 ppm (GC) |
| color【颜色】 | white |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
