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Anti-C-Reactive Protein antibody produced in chicken
产品编号: | 4092652 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 50 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-C-Reactive Protein antibody produced in chicken
Anti-CRP
基本信息
MDL number | MFCD00162183 |
NACRES | NA.41 |
General description【一般描述】 | C-reactive protein (CRP) is a member of a protein family that serve as soluble pattern recognition molecules. This protein is generated and liberated in the circulation in response to infection and tissue damage. CRP gene is located on human chromosome 1q23.2. CRP is synthesized by human peripheral blood mononuclear cells. The CRP gene is localized to chromosome 1. |
Immunogen【免疫原】 | C-reactive protein. Immunogen Sequence: GI # 30213, sequence 1-224 |
Application【应用】 | Anti-C-Reactive Protein antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200. It is also suitable for indirect ELISA. |
Biochem/physiol Actions【生化/生理作用】 | C-Reactive Protein (CRP) is a homopentamer that belongs to the pentaxin family. CRP binds to phosphorylcholine in a calcium dependent manner and plays a key role in host defense. It is involved in several defense mechanisms such as, agglutination, bacterial capsular swelling, phagocytosis and complement fixation. CRP interacts with secreted M-ficolin anchored to monocyte transmembrane G protein-coupled receptor 43 and mediates immune signaling and regulates host defense. It scavenges nuclear waste that is released from cells following apoptosis. C-reactive protein (CRP) plays a major role the early stages of atherosclerosis and pantothenic acid (PA). It shows an antioxidant effect in inflammatory process. The active monomeric form of C-reactive protein (CRP) is involved in proinflammatory functions. |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
biological source【生物来源】 | chicken |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
manufacturer/tradename | Genway 15-288-10072F |
technique(s) | indirect ELISA: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | CAA40020.1 |
UniProt accession no.【UniProt登记号】 | P02741 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... CRP(1401) |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |