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Anti-Ly-6G (mouse), violetFluor® 450, clone RB6-8C5 Antibody
产品编号: | 4091183 |
规格: | clone RB6-8C5, from rat, violetFluor® 450 |
包装规格: | 25 μG,100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Ly-6G (mouse), violetFluor® 450, clone RB6-8C5 Antibody
Lymphocyte antigen 6G (Ly-6G), Ly-6G.1, Ly-6G
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | The RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the RB6-8C5 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes.Note: The RB6-8C5 antibody has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C. Other reports suggest that this antibody is specific for Ly-6G, without cross-reactivity for Ly-6C (Nagendra S. and Schlueter AJ. 2003. Cytometry A, 58(2): 195-200. |
Immunogen【免疫原】 | Immunogen information for this antibody is proprietary information. |
Application【应用】 | Research Sub Category Immunoglobulins & Immunology Anti-Ly-6G (mouse), violetFluor® 450, clone RB6-8C5 Antibody is an antibody against Ly-6G for use in Flow Cytometry. Research Category Inflammation & Immunology |
Quality【质量】 | This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. Flow Cytometry Analysis: 0.06 μg from a representative lot detected Ly-6G in one million C57Bl/6 bone marrow cells. |
Physical form【外形】 | Purified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2. Purified by size-exclusion chromatography |
Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
Legal Information【法律信息】 | violetFluor is a registered trademark of Tonbo Biotechnologies |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | rat |
conjugate【偶联物】 | violetFluor® 450 |
antibody form【抗体形式】 | purified antibody |
antibody product type | primary antibodies |
clone【克隆】 | RB6-8C5, monoclonal |
species reactivity | mouse |
packaging【包装】 | antibody small pack of 25 μg |
technique(s) | flow cytometry: suitable |
isotype【同位素/亚型】 | IgG2bκ |
UniProt accession no.【UniProt登记号】 | P35461 |
产品说明
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |