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Anti-phospho-Raptor (Thr706) Antibody
产品编号: | 4090246 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μg |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-phospho-Raptor (Thr706) Antibody
P150 target of rapamycin (TOR)-scaffold protein, p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats, regulatory associated protein of mTOR
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Raptor is a subunit of mTORC1 which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Within mTORC1, Raptor positively regulates mTORC1 activity and functions as a scaffold for recruiting mTORC1 substrates. |
Specificity【特异性】 | This antibody recognizes Raptor phosphorylated at Thr706. |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human Raptor phosphorylated at and around Thr706. Epitope: Ser706 |
Application【应用】 | Detect phospho-Raptor (Thr706) using this Anti-phospho-Raptor (Thr706) Antibody validated for use in WB, DB. |
Quality【质量】 | Evaluated by Dot Blot in modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein. Dot Blot Analysis: 1 µg/mL of this antibody detected Raptor in modified and non-modified peptides of phosphorylated and non-phosphorlyated Raptor protein. |
Physical form【外形】 | Affinity purified Purified rabbit serum in PBS with 0.05% sodium azide. |
Analysis Note【分析说明】 | Control Modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | human, canine |
species reactivity (predicted by homology) | mouse (based on 100% sequence homology), rat (based on 100% sequence homology), bovine (based on 100% sequence homology), dog (based on 100% sequence homology), horse (based on 100% sequence homology) |
technique(s) | dot blot: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_065812 |
UniProt accession no.【UniProt登记号】 | Q8N122 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~ 150 kDa |
【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 2 |