您的位置：首页 > 产品中心 > Anti-SAP30 (yeast) Antibody
Anti-SAP30 (yeast) Antibody
产品别名
Anti-SAP30 (yeast) Antibody
Sin3 corepressor complex subunit SAP30, Sin3-associated polypeptide, 30 kDa, Sin3-associated polypeptide, 30kDa, Sin3A-associated protein, 30kDa, histone deacetylase complex subunit SAP30
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | SAP30 (Sin3A-associated protein) is a widely expressed nuclear protein that is functionally conserved between human and yeast. It is a component of the multiprotein histone deacetylase complex containing the transcriptional repressor Sin3, multiple histone deacetylases (HDAC1 and HDAC2), histone binding proteins (RbAp46 and RbAp48) and other polypeptides. SAP30 can recruit the deacetylase complex to promoter DNA in a Sin3 independent manner and is involved in the recruitment of the mSin3 complex to a specific subset of N-CoR corepressor complexes. The latter function suggests a role for SAP30 in N-CoR-mediated repression. Furthermore, SAP30 may be involved in imparting target specificity to the deacetylase complex. |
| Specificity【特异性】 | Not tested in other species. Recognizes yeast SAP30 at ~27 kDa. |
| Immunogen【免疫原】 | Immunogen was a synthetic peptide corresponding to a.a. 141-157 of yeast SAP30, conjugated to KLH. Epitope: a.a. 141-157 |
| Application【应用】 | Research Category Epigenetics & Nuclear Function Research Sub Category Histones Chromatin Biology Anti-SAP30 (yeast) Antibody is a Rabbit Polyclonal Antibody for detection of SAP30 (yeast) also known as Sin3 corepressor complex subunit SAP30 & has been validated in WB. |
| Quality【质量】 | Western Blot Analysis: 1 μg/ml of this antibody detected SAP30 in a yeast extract. |
| Physical form【外形】 | Protein A purified IgG in 0.1M Tris-Glycine (pH7.4) 150 mM NaCl with 0.05% NaN3. Format: Purified |
| Analysis Note【分析说明】 | Control Yeast extract |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 300 |
| biological source【生物来源】 | rabbit |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | Saccharomyces cerevisiae |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NM_003864.3 |
| UniProt accession no.【UniProt登记号】 | P38429 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~27 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of shipment. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
