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Fmoc-Cys(Trt)-OH
产品编号: | 4089756 |
规格: | Novabiochem® |
CAS NO: | 103213-32-7 |
包装规格: | 25 G,100 G,250 G,500 G,5 KG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4089756 | 25 G | 732 | |||
4089756 | 100 G | 1760 | |||
4089756 | 250 G | 3180 | |||
4089756 | 500 G | 6110 | |||
4089756 | 5 KG | 53580 |
产品别名
103213-32-7
Fmoc-Cys(Trt)-OH
N-α-Fmoc-S-trityl-L-cysteine
基本信息
Empirical Formula【经验(实验)分子式】 | C37H31NO4S |
Molecular weight | 585.71 |
MDL number | MFCD00038538 |
General description【一般描述】 | The standard derivative for Fmoc SPPS of peptides containing Cys [1]. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation [2,3] to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP®, is to be employed, it is strongly recommended that collidine is used as the base [4], as this has been shown to significantly reduce loss of optical integrity during coupling. The product number for this product was previously 04-12-1018. To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”. |
Linkage【联系】 | Replaces: 04-12-1018 |
Analysis Note【分析说明】 | Colour (visual): white to off white Appearance of substance (visual): powder Colour index (0,5 M in DMF): ≤ 150 Hazen Identity (IR): passes test Enantiomeric purity: ≥ 99.5 % (a/a) Purity (HPLC): ≥ 99.0 % (a/a) Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a) Fmoc-ß-Ala-Cys (Trt) -OH (HPLC): ≤ 0.1 % (a/a) Fmoc-Cys(Trt)-Cys(Trt)-OH (HPLC): ≤ 0.1 % (a/a) Fmoc-Cys-OH (HPLC): ≤ 0.1 % (a/a) Assay free amino acid (HPLC): ≤ 0.2 % Purity (TLC(011A)): ≥ 98 % Purity (TLC(0811)): ≥ 98 % Solubility (1 mmole in 2 ml DMF): clearly soluble Assay (acidimetric): ≥ 98.0 % Water (K. F.): ≤ 2.0 % Ethyl acetate (HS-GC): ≤ 0.5 % Acetate (IC): ≤ 0.02 % For TLC-Systems see our General Catalog |
Legal Information【法律信息】 | Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 400 |
product line【产品线】 | Novabiochem® |
Assay【测定】 | ≥98% (TLC) ≥98.0% (acidimetric) ≥99.0% (HPLC) |
form【形式】 | powder |
reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
manufacturer/tradename | Novabiochem® |
mp | 164-175 ℃ |
application(s) | peptide synthesis |
functional group【官能团】 | Fmoc |
storage temp.【储存温度】 | 15-25℃ |
InChI | 1S/C37H31NO4S/c39-35(40)34(38-36(41)42-24-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)25-43-37(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,38,41)(H,39,40)/p-1/t34-/m0/s1 |
InChI key | KLBPUVPNPAJWHZ-UMSFTDKQSA-M |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |