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Anti-Phosphothreonine-Proline Antibody

产品编号:4088528
规格:from rabbit, purified by affinity chromatography
包装规格:100 μg
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4088528100 μg5010
基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Phosphothreonine-Proline, along with similar motifs involving serine/threonine residues preceding proline undergoing phosphorylation, has critical roles in the moderation of various cellular processes, protein function, and kinases through proline-directed phosphorylation. The deregulation of proline-directed phosphorylation is known to be a factor in diseases such as cancer and Alzheimer’s neurodegeneration.
Specificity【特异性】
Recognizes the phosphorylated phothreonine-proline motif, which is the site of phosphorylation of many proline-directed protein kinase such MAPK and cyclin-dependent protein kinases. Also recognizes the phosphoserine-proline motif to a similar degree.
Immunogen【免疫原】
KLH-phosphothreonine-proline amide
(pT-P-NH2) peptide conjugates
Application【应用】
Detect Phosphothreonine-Proline using this Anti-Phosphothreonine-Proline Antibody validated for use in WB.
Quality【质量】
Evaluated by Western Blot in Calyculin treated Jurkat cell lysate.
Western Blot Analysis: 1:500 dilution of this lot detected phosphorylated proteins on 10 μg of calyculin treated Jurkat lysates.
Linkage【联系】
Replaces: AB3192
Physical form【外形】
Liquid in TBS with 0.05% sodium azide and 50% glycerol.
Affinity purified
Analysis Note【分析说明】
Control
Calyculin treated Jurkat cell lysate
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
rat, human, mouse
technique(s)
western blot: suitable
shipped in【运输】
wet ice
产品说明
Storage and Stability【储存及稳定性】
Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
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