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Anti-SIRT4 Antibody
| 产品编号： | 4087772 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-SIRT4 Antibody
NAD-dependent protein deacetylase sirtuin-4, NAD-dependent ADP-ribosyltransferase sirtuin-4
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | NAD-dependent protein deacetylase sirtuin-4 (SIRT4) is also called NAD-dependent ADP-ribosyltransferase sirtuin-4 and SIR2-like protein 4 (SIR2L4). SIRT4 catalyzes the transfer of ADP-ribosyl groups onto target proteins, and has been shown to inhibit GLUD1 enzyme activity, down-regulate insulin secretion and is involved in chromatin silencing. SIRT4 is believed to be a transcriptional regulator in embyonic stem cell and hematopoietic stem cells. SIRT4 is widely expressed and has been detected in vascular smooth muscle and striated muscle, and pancreatic (islets of Langerhans) insulin-producing beta-cells. |
| Specificity【特异性】 | This antibody is predicted to not cross-react with other Sirtuin family members. |
| Immunogen【免疫原】 | KLH-conjugated synthetic peptide corresponding to the N-terminus of human SIRT4. Epitope: N-terminus |
| Application【应用】 | Anti-SIRT4 Antibody detects level of SIRT4 & has been published & validated for use in SIRT4. Research Sub Category Cell Cycle, DNA Replication & Repair Research Category Epigenetics & Nuclear Function |
| Quality【质量】 | Evaluated by Western Blotting in human liver tissue lysate. Western Blotting Analysis: 1 μg/mL of this antibody detected SIRT4 in human liver tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. Antigen Affinity Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q9Y6E7 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... SIRT4(23409) |
产品说明
| Target description【目标描述】 | ~38 kDa observed. Uncharacterized bands may be observed in some lysate(s). |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
