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产品别名
Anti-PACSIN1 Antibody, NT
protein kinase C and casein kinase substrate in neurons 1, syndapin I
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | PACSINs, also known as syndapins, are a protein family consisting of three members that have been implicated in synaptic vesicular membrane trafficking and regulation of dynamin-mediated endocytotic processes (Cuajungco, 2006). It is presumed that all isoforms bind Dynamin, Synaptojanin 1 and N-WASP through their Src homology 3 domains. While PACSIN1 appears to be restricted to neural tissues, two PACSINs are more widespread with PACSIN2 being ubiquitously expressed and PACSIN3 present mainly in skeletal muscle, heart and lung (Modregger, 2001). PACSIN1 has been implicated as playing a central role in synaptic vesicle recycling (Kessels, 2004). Expected molecular weight is 51 kDa. |
| Specificity【特异性】 | Reactivity with other species has not been tested. The antibody recognizes human PACSIN1. |
| Immunogen【免疫原】 | KLH conjugated synthetic peptide selected from the N-terminal region of human PACSIN1. |
| Application【应用】 | Anti-PACSIN1 Antibody, N-terminus detects level of PACSIN1 & has been published & validated for use in WB, IH(P). |
| Quality【质量】 | Evaluated on a representative lot by Western blot on mouse brain lysate using a 1:100 - 1:500 dilution of Anti-PACSIN1. |
| Physical form【外形】 | PBS containing 0.09% NaN3. Format: Purified Protein G Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | mouse, human |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q9BY11 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~57 kDa |
| Storage and Stability【储存及稳定性】 | Maintain at 2-8ºC for up to 6 months from date of receipt. -20ºC is recommended for long term storage. |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
