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Anti-Nicotinic Acetylcholine Receptor β2 Antibody
产品编号: | 4087741 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Nicotinic Acetylcholine Receptor β2 Antibody
Neuronal nicotinic acetylcholine receptor beta 2
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Nicotinic acetylcholine receptors, also known as nAChRs, belong to a family of proteins called ligand gated ion channels and are widely expressed throughout the nervous system. nAChRs are made up of 5 subunits (two α and three β). Subunits α4 and β2 (α4β2) is the main receptor in the mammalian brain and has been associated with the positive reinforcing effects of nicotine. The relative contribution of nAChRs β2 and β4 are not well understood because the subunit structure that mediates synaptic transmission in the peripheral nervous system is unknown. |
Specificity【特异性】 | This antibody recognizes Nicotinic Acetylcholine Receptor β2. |
Immunogen【免疫原】 | This antibody is generated from rabbits immunized with a KLH-conjugated linear peptide selected from residues of Nicotinic Acetylcholine Receptor β2. |
Application【应用】 | Detect Nicotinic Acetylcholine Receptor β2 using this Anti-Nicotinic Acetylcholine Receptor β2 Antibody validated for use in WB. |
Quality【质量】 | Routinely evaluated by Western Blot in rat e16 brain lysate. Western Blot Analysis: : 1:20,000 dilution of this lot detected Nicotinic Acetylcholine Receptor β2 on 10 µg of rat e16 brain lysate. |
Other Notes【其他说明】 | Affinity purified |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | mouse, human, rat |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_062170 |
UniProt accession no.【UniProt登记号】 | P17787 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | Approx. 55 kDa |
【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |