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Anti-Slitrk3 Antibody
| 产品编号： | 4087449 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Slitrk3 Antibody
SLIT, NTRK-like family 3, Slitrk3
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | SLIT and NTRK-like family 3 (Slitrk3) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Overexpression of Slitrk3 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. |
| Specificity【特异性】 | This antibody is predicted to have no cross-reactivity to other Slitrk proteins. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human Slitrk3. |
| Application【应用】 | This Slitrk3 antibody is validated for use in WB & IHC for the detection of the Slitrk3 protein. Research Category Neuroscience Neuroscience Research Sub Category Developmental Neuroscience Neurofilament & Neuron Metabolism Immunohistochemistry Analysis: Human brain tissue was prepared using heat-induced epitope retrieval (HIER). Immunostaining was performed using 2.5 µg/mL Slitrk3 antibody. |
| Quality【质量】 | Evaluated by Western Blot in SK-N-SH cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected Slitrk3 in 15 µg of SK-N-SH cell lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control SK-N-SH cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | O94933 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~120 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
