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产品别名
Anti-FoxP1 Antibody
forkhead box P1, fork head-related protein like B, glutamine-rich factor 1
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Forkhead Box P1 (FoxP1) is a member of the FOX family of transcription factors. This protein is known to forms homodimers and heterodimers with family members FoxP2 and FoxP4. The forkhead box family has a broad range of functions. These proteins play important roles in immune response, organ development and the development of cancer. The FoxP1 protein is widely expressed and contains both forkhead (winged-helix) and C2H2 zinc finger nucleic acid-binding motifs. At least four different isoforms that result from alternative splicing of the mRNA transcript have been reported. |
Specificity【特异性】 | This antibody recognizes FoxP1. |
Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to mouse FoxP1. Epitope: Unknown |
Application【应用】 | Research Sub Category Transcription Factors Developmental Signaling Research Category Epigenetics & Nuclear Function Epigenetics & Nuclear Function Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected FoxP1 in HeLa and NIH/3T3 cells. Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in IH. (Lu, M.M., et al. (2002). Mechanisms of Development 119S:S197–S202.) Use Anti-FoxP1 Antibody (Rabbit Polyclonal Antibody) validated in ICC, WB, IHC to detect FoxP1 also known as forkhead box P1, fork head-related protein like B, glutamine-rich factor 1. |
Quality【质量】 | Evaluated by Western Blot in RAW264.7 cell lysate. Western Blot Analysis: 1:1,000 dilution of this antibody detected FoxP1 on 10 µg of RAW264.7 cell lysate. |
Physical form【外形】 | Unpurified rabbit polyclonal serum with 0.05% sodium azide. Unpurified |
Analysis Note【分析说明】 | Control RAW264.7 cell lysate |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | serum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
species reactivity | mouse, human |
technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable |
isotype【同位素/亚型】 | IgG |
NCBI accession no.【NCBI登记号】 | NP_444432 |
UniProt accession no.【UniProt登记号】 | P58462 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | 79 kDa observed. Alternative splicing can result in cell type dependent isoforms. |
Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |