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ZQ-16
产品别名
376616-73-8
ZQ-16
2-(Hexylthio)-6-hydroxy-4(3H)-pyrimidinone
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C10H16N2O2S |
Molecular weight | 228.31 |
PubChem Substance ID【PubChem化学物质编号】 | 329825987 |
Biochem/physiol Actions【生化/生理作用】 | ZQ-16 is a potent and selective agonist for medium-chain free fatty acid receptor GPR84 (G protein-coupled receptor 84). ZQ-16 activates GPR84-mediated calcium mobilization, inhibition of cAMP accumulation, phosphorylation of ERK1/2, receptor desensitization and internalization, and receptor-β-arrestin interaction. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 5 mg/mL, clear (warmed) |
storage temp.【储存温度】 | room temp |
SMILES string | CCCCCCSC1=NC(O)=CC(O)=N1 |
InChI | 1S/C10H16N2O2S/c1-2-3-4-5-6-15-10-11-8(13)7-9(14)12-10/h7H,2-6H2,1H3,(H2,11,12,13,14) |
InChI key | UYXOAKRMLQKLQX-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H315 - H319 - H335 |
Precautionary Statements | P305 + P351 + P338 |
Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
Target Organs【靶器官】 | Respiratory system |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |