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Eupatilin
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4086721 | 5 MG | 1210 | |||
4086721 | 25 MG | 5620 |
产品别名
22368-21-4
Eupatilin
2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one
NSC 122413
5,7-Dihydroxy-3′,4′,6-trimethoxyflavone
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C18H16O7 |
Molecular weight | 344.32 |
MDL number | MFCD13194819 |
PubChem Substance ID【PubChem化学物质编号】 | 329826018 |
NACRES | NA.77 |
Application【应用】 | Eupatilin has been used to investigate its inhibitory effects on intracranial hemorrhage (ICH)-induced inflammation and its anti-inflammatory mechanisms in mouse BV2 cells, in vitro. It has also been used as a standard for its quantitative estimation in Artemisia extracts by microcolumn high performance liquid chromatography with diode array (HPLC-DAD) assay. |
Biochem/physiol Actions【生化/生理作用】 | Eupatilin is an important constituent in the leaves of Artemisia argyi and also an active component of DA-9601. It exhibits anti-apoptotic effects. Eupatilin provides protection against tumor necrosis factor α (TNF-α)-mediated inflammation in human umbilical vein endothelial cells. It is used in the treatment of gastritis and peptic ulcers. Eupatilin safeguards gastric epithelial cells from oxidative damage and smooth muscle cells from indomethacin-induced cell damage. Eupatilin lowers bile acid-stimulated hepatocyte apoptosis. Eupatilin is a flavone with anti-oxidative, anti-inflammatory, and anti-cancer properties. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | (Isolated from Artemisia sp.) |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
storage condition【储存条件】 | desiccated protect from light |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 20 mg/mL, clear |
storage temp.【储存温度】 | −20℃ |
SMILES string | O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(O)=C(OC)C(O)=C31 |
InChI | 1S/C18H16O7/c1-22-12-5-4-9(6-14(12)23-2)13-7-10(19)16-15(25-13)8-11(20)18(24-3)17(16)21/h4-8,20-21H,1-3H3 |
InChI key | DRRWBCNQOKKKOL-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |