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海葱次苷
Proscillaridin A
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4086344 | 5 MG | 1390 | |||
4086344 | 25 MG | 5320 |
产品别名
466-06-8
海葱次苷
Proscillaridin A
Scillarenin 3β-rhamnoside
(3β)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-14-hydroxybufa-4,20,22-trienolide
3-(6-Deoxy-α-
海葱苷 3β-鼠李糖甙
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C30H42O8 |
Molecular weight | 530.65 |
MDL number | MFCD00214065 |
Biochem/physiol Actions【生化/生理作用】 | Proscillaridin A, a cardiac glycoside, is an antiarrhythmic drug that enhances DNMT inhibitors and HDAC inhibitors activity. Combination of decitabine with proscillaridin A produced profound gene expression reprogramming associated with down-regulation of 153 epigenetic regulators including SYMD3 and KDM8. Proscillaridin A was recently identified as a potent anti-HBV agent (IC50 = 7.2?nM). |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥90% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | −20℃ |
SMILES string | C[C@]12CC[C@]3([H])[C@@]4(C)CC[C@H](O[C@]5([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)C=C4CC[C@@]3([H])[C@@]1(O)CC[C@@H]2C6=COC(C=C6)=O |
InChI | 1S/C30H42O8/c1-16-24(32)25(33)26(34)27(37-16)38-19-8-11-28(2)18(14-19)5-6-22-21(28)9-12-29(3)20(10-13-30(22,29)35)17-4-7-23(31)36-15-17/h4,7,14-16,19-22,24-27,32-35H,5-6,8-13H2,1-3H3/t16-,19?,20?,21?,22?,24-,25+,26+,27-,28?,29?,30?/m0/s1 |
InChI key | MYEJFUXQJGHEQK-RLQJMXQZSA-N |
安全信息
Pictograms【象形图】 | GHS06 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H301 |
Precautionary Statements | P301 + P310 + P330 |
Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
WGK | WGK 3 |