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2′-MeCCPA
产品别名
205171-12-6
2′-MeCCPA
2′-Me-CCPA
2-Chloro-N-cyclopentyl-2′-C-methyladenosine
2-Chloro-2′-C-methyl-N6-cyclopentyladenosine
基本信息
Empirical Formula【经验(实验)分子式】 | C16H22ClN5O4 |
Molecular weight | 383.83 |
Biochem/physiol Actions【生化/生理作用】 | 2′-MeCCPA is a potent and A1-selective adenosine receptor agonist (Ki = 1.8 nM/bovine A1, 3.9 μM/bovine A2a, 5.0 μM/rat A3). 2′-MeCCPA inhibits 100 μM forskolin-induced adenylate cyclase activity in rat cortical membrane preparations (IC50 = 13.1 nM; ECmax = 15.1% inhibition) without antagonist potency against A1 agonist CHA (N6-cyclohexyladenosine). |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |