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Calretinin from mouse
产品编号: | 4085278 |
规格: | recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC) |
包装规格: | 5 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Calretinin from mouse
Calb2
calbindin 2
Calretinin
CR
产品性质
biological source【生物来源】 | mouse |
recombinant【重组】 | expressed in E. coli |
Assay【测定】 | ≥90% (HPLC) ≥90% (SDS-PAGE) |
form【形式】 | solution |
mol wt【分子量】 | ~57 kDa |
packaging【包装】 | pkg of 5 μg |
storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
impurities【杂质】 | endotoxin, tested |
NCBI accession no.【NCBI登记号】 | Q08331 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −70℃ |
Gene Information | mouse ... Calb2(12308) |
基本信息
General description【一般描述】 | Calretinin is a Ca2+-binding protein. It belongs to the EF-hand family. This gene is upregulated in reactive mesothelial cells and in malignant mesothelioma. Recombinant mouse Calretinin protein is expressed from Escherichia coli and purified by proprietary chromatographic techniques. |
Biochem/physiol Actions【生化/生理作用】 | Calretinin is widely distributed in the brain and might be responsible for neural protection. It regulates calcium signaling in neurons. Absence of calretinin in mice negatively affects long-term potentiation, motor coordination and Purkinje cell activity. |
Physical form【外形】 | 50 ml (100 μg/ml) in 50 mM Tris-Acetate, pH 7.5, 1 mM EDTA, 20% Glycerol. |
Reconstitution【重悬】 | Centrifuge the vial prior to opening. Avoid freeze-thaw cycles. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 3 |