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InSolution Wnt Antagonist II, IWP-2-CAS 686770-61-6-Calbiochem
| 产品编号： | 4083685 |
| 规格： | A 10 mM (5 mg/1.07 ml) sterile-filtered solution of Wnt Antagonist II, IWP-2) in DMSO. |
| CAS NO： | 686770-61-6 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4083685 | 5 MG | 1500 |
产品别名
686770-61-6
InSolution Wnt Antagonist II, IWP-2-CAS 686770-61-6-Calbiochem
N-(6-Methylbenzo[d]thiazol-2-yl)-2-(4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-ylthio)acetamide, Wnt Pathway Inhibitor II InSolution, Inhibitor of Wnt Production-2, Porcn Inhibitor I InSolution, InSolution Wnt Antag
基本信息
| Empirical Formula【经验(实验)分子式】 | C22H18N4O2S3 |
| Molecular weight | 466.60 |
| MDL number | MFCD04457599 |
| General description【一般描述】 | A cell-permeable benzothiazolyl-acetamide compound that inhibits the cellular Wnt processing and secretion via selective blockage of MBOAT (membrane-bound O-acyltranferase) family member Porcn- (Porcupine) mediated Wnt palmitoylation. IWP-2 does not affect Wnt/β-catenin signaling pathway in general and, unlike IWR-1-endo (Cat. No. 681669), displays no effect against Wnt-stimulated cellular responses. |
| Biochem/physiol Actions【生化/生理作用】 | Cell permeable: yes Primary Target Porcn Reversible: yes |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Physical form【外形】 | A 10 mM (5 mg/1.07 ml) sterile-filtered solution of Wnt Antagonist II, IWP-2 (Cat. No. 681671) in DMSO. |
| Reconstitution【重悬】 | Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C. Slight warming may be required upon initial thaw. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Assay【测定】 | ≥99% (HPLC) |
| Quality Level【质量水平】 | 100 |
| form【形式】 | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze avoid repeated freeze/thaw cycles desiccated (hygroscopic) protect from light |
| storage temp.【储存温度】 | −70℃ |
| packaging【包装】 | Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
| Flash Point(F)【闪点(F)】 | 188.6 °F - (refers to pure substance) |
| Flash Point(C)【闪点(C)】 | 87 ℃ - (refers to pure substance) |
