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Anti-TLS Antibody, clone 1FU-1D2
| 产品编号： | 4082534 |
| 规格： | ascites fluid, clone 1FU-1D2, from mouse |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-TLS Antibody, clone 1FU-1D2
75 kDa DNA-pairing protein, FUS-CHOP fusion protein, FUS-CHOP protein fusion, Fusion gene in myxoid liposarcoma, Oncogene FUS, Oncogene TLS, Translocated in liposarcoma protein, fus-like protein, fus/tls-chop oncogene, fusion (involved in t(12, 16) in ma
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | The TLS/FUS protein contains an RNA-recognition motif and is a component of nuclear riboprotein complexes. It resembles a transcription factor in that it binds DNA, contributes a transcriptional activation domain to the FUS-ERG oncoprotein, and interacts with several transcription factors in vitro. It binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. It may play a role in maintenance of genomic integrity. |
| Specificity【特异性】 | This antibody recognizes TLS. |
| Immunogen【免疫原】 | Linear peptide corresponding to human TLS. Epitope: Unknown |
| Application【应用】 | Research Sub Category RNA Metabolism & Binding Proteins Transcription Factors Use Anti-TLS Antibody, clone 1FU-1D2 (Mouse Monoclonal Antibody) validated in WB, ICC to detect TLS also known as 75 kDa DNA-pairing protein, FUS-CHOP fusion protein. Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected TLS in C2C12 cells. Research Category Epigenetics & Nuclear Function Epigenetics & Nuclear Function |
| Quality【质量】 | Evaluated by Western Blot in HepG2 cell lysate. Western Blot Analysis: 1:1,000 dilution of this antibody detected TLS on 10 µg of HepG2 cell lysate. |
| Physical form【外形】 | Unpurified Unpurified mouse monoclonal IgG1κ preservative-free ascites. |
| Analysis Note【分析说明】 | Control HepG2 cell lysate |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | 1FU-1D2, monoclonal |
| species reactivity | human, mouse, rat |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_004951.1 |
| UniProt accession no.【UniProt登记号】 | P35637 |
| shipped in【运输】 | dry ice |
| Gene Information | human ... FUS(2521) |
产品说明
| Target description【目标描述】 | Observed at 65 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
