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Anti-Olig2 Antibody, clone 211F1.1, Alexa Fluor®488 Conjugate | MABN50A4
| 产品编号： | 4082420 |
| 规格： | clone 211F1.1, from mouse, ALEXA FLUOR® 488 |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Olig2 Antibody, clone 211F1.1, Alexa Fluor®488 Conjugate | MABN50A4
Oligodendrocyte transcription factor 2, Oligo2, Class B basic helix-loop-helix protein 1, bHLHb1, Class E basic helix-loop-helix protein 19, bHLHe19, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Oligodendrocyte lineage transcription factor 2 (Olig2) is a protein belonging to group A of the OLIG family of basic helix-loop-helix transcription factors (bHLH). bHLH proteins are divided into 6 groups (A-F), and characterized by their biochemical properties and structure. Olig2 is classified as group A due to its ability to form heterodimers with other bHLH proteins and binding to the E box. Olig2 has a crucial role during development in specifying the final location of motor neurons and oligodendrocytes in the spinal cord, along with the development within the hindbrain of somatic motor neurons. Olig2 expression is observed within oligodendrocytes and in developing astrocytes. Recent studies have shown strong expression of Olig2 in human oligodendrogliomas, primary tumors within the central nervous system, and moderate expression in astrocytomas. These observations have led to the proposal of Olig2 having potential as an oligodendroglioma diagnostic marker. |
| Immunogen【免疫原】 | Recombinant protein corresponding to human Olig2. |
| Application【应用】 | Research Category Neuroscience Research Sub Category Developmental Neuroscience |
| Quality【质量】 | Evaluated by Immunocytochemistry in rat oligodendrocyte precursor cells. Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Olig2 in rat oligodendrocyte precursor cells. |
| Physical form【外形】 | Purified mouse monoclonal IgG2a conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA. Protein G Purified |
| Analysis Note【分析说明】 | Control Rat oligodendrocyte precursor cells |
| Legal Information【法律信息】 | ALEXA FLUOR is a registered trademark of Life Technologies |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | ALEXA FLUOR® 488 |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 211F1.1, monoclonal |
| species reactivity | mouse, rat |
| species reactivity (predicted by homology) | human (based on 100% sequence homology) |
| technique(s) | immunocytochemistry: suitable |
| isotype【同位素/亚型】 | IgG2a |
| NCBI accession no.【NCBI登记号】 | NP_005797 |
| UniProt accession no.【UniProt登记号】 | Q13516 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... OLIG2(10215) |
产品说明
| Target description【目标描述】 | The unconjugated parent antibody (Cat. No. MABN50) has an observed molecular weight at ~37 kDa |
| Storage and Stability【储存及稳定性】 | Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
