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纤连蛋白 溶液 来源于人类成纤维细胞
Fibronectin human foreskin fibroblasts
| 产品编号： | 4081699 |
| 规格： | lyophilized powder, suitable for cell culture |
| 包装规格： | 0.5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
纤连蛋白 溶液 来源于人类成纤维细胞
Fibronectin human foreskin fibroblasts
fibronectin
基本信息
| EC number【EC 号】 | 289-149-2 |
| MDL number | MFCD00131062 |
| NACRES | NA.75 |
| General description【一般描述】 | Fibronectin 1 (FN1) is a glycoprotein of the extracellular matrix that is coded by FN1 gene. It is expressed in the plasma and at the cell surface. It is mapped to human chromosome 2q35. Fibronectin is mostly synthesized by fibroblasts and endothelial cells. |
| Application【应用】 | Epithelial cells, mesenchymal cells, neuronal cells, fibroblasts, neural crest cells, endothelial cells Fibronectin human foreskin fibroblasts has been used in extracellular matrix binding assay and probiglycan and cleavage assays. It has also been used in ectoderm (neuronal) differentiation and in the preparation of a semi-solid growth medium. |
| Biochem/physiol Actions【生化/生理作用】 | Fibronectin 1 (FN1) participates in cell adhesion, growth, migration, wound healing, blood coagulation and metastasis. Mutations in FN1 results in glomerulopathy. It plays an important role in cell attachment and spreading, control of cell cytoskeleton, morphology and differentiation. FN1 is also involved in extracellular matrix formation, hemostasis and thrombosis. Fibronectin production by normal human foreskin fibroblasts has been shown to improve two-fold after glucocorticoid treatment. |
| Caution【注意】 | 本品复原后，不建议涡漩、过度搅拌、反复冻融。 |
| Physical form【外形】 | Lyophilized in CAPS buffered saline |
| Preparation Note【制备说明】 | dialyzed against chloroform |
| Reconstitution【重悬】 | Store reconstituted solution in working aliquots at -20℃ or lower. |
| Analysis Note【分析说明】 | 蛋白质均一性由免疫电泳评估。 |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | human foreskin fibroblasts |
| product line【产品线】 | BioReagent |
| form【形式】 | lyophilized powder |
| mol wt【分子量】 | ~550 kDa |
| technique(s) | cell culture | mammalian: suitable |
| surface coverage【表面覆盖度】 | 1‑5 μg/cm2 |
| solubility【溶解性】 | H2O: 1 mg/mL at 37 ℃ (Store reconstituted solution in working aliquots at -20℃ or lower.) |
| web metadata keyword.default | attachment factor, mesenchymal cell attachment, neuronal cell attachment, fibroblast attachment, neural crest cell attachment, endothelial cell attachment |
| UniProt accession no.【UniProt登记号】 | P02751 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... FN1(2335) |
| packaging【包装】 | 0.5 mg in serum bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
