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W146

产品编号:4076088
规格:(R)-3-Amino-(3-hexylphenylamino)-4-oxobutylphosphonic acid (TFA salt), powder
CAS NO:909725-62-8
包装规格:1 MG,10 MG
产品类别:进口试剂
品牌:Avanti
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
40760881 MG3130
407608810 MG19920
产品别名

909725-62-8

W146

S1P1 Antagonist

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C18H28F3N2O6P
Molecular weight
456.39
NACRES
NA.25
General description【一般描述】
W146 is a sphingosine-1-phosphate 1 (S1P1) selective antagonist.
Compound 2a is a selective antagonist for human S1P1 (hS1P1) receptor activation by the physiological agonist S1P.
Application【应用】
W146 has been used:
  • to verify the mode of action of sphingosine-1-phosphate (S1P) in human bone marrow derived mesenchymal stem cells (hMSCs ) and primary human hepatogenic profibrotic cells (hHPCs)
  • to study oxidative stress and drug treatment in granulosa cells
  • to evaluate its effects on transendothelial electrical resistance (TEER)

Biochem/physiol Actions【生化/生理作用】
W146 acts as an orthosteric antagonist. It is linked to blood lymphopenia and lung edema in mice.
产品性质
Assay【测定】
>99% (TLC)
form【形式】
powder
manufacturer/tradename
Avanti Polar Lipids 857390P
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
packaging【包装】
5 mL Amber Glass Screw Cap Vial (857390P-10mg)
5 mL Amber Glass Screw Cap Vial (857390P-1mg)
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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